1H-Indole-3-carboxylicacid, 7-Methoxy- - Names and Identifiers
1H-Indole-3-carboxylicacid, 7-Methoxy- - Physico-chemical Properties
Molecular Formula | C10H9NO3
|
Molar Mass | 191.18 |
Density | 1.381g/cm3 |
Boling Point | 447.6°C at 760 mmHg |
Flash Point | 224.5°C |
Vapor Presure | 8.54E-09mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.677 |
1H-Indole-3-carboxylicacid, 7-Methoxy- - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
1H-Indole-3-carboxylicacid, 7-Methoxy- - Introduction
7-Methoxy-1H-indole-3-carboxylic acid is an organic compound with the chemical formula C12H11NO3. The following is a brief description of its nature, use, preparation and safety information:
Nature:
-Appearance: 7-Methoxy-1H-indole-3-carboxylic acid is a white to pale yellow crystalline solid.
-Melting point: about 132-134 ℃.
-Solubility: Soluble in common organic solvents, such as ethanol, chloroform and dichloromethane. Slightly soluble in water.
Use:
-7-Methoxy-1H-indole-3-carboxylic acid is an important intermediate in organic synthesis.
-It can be used to synthesize compounds with different biological activities, such as drugs, plant pesticides and dyes.
-The structure of the compound contains indole ring and carboxylic acid functional group, which makes it have potential application value in the field of pharmacy and pesticide.
Preparation Method:
The preparation of-7-methoxy-1H-indole-3-carboxylic acid is usually achieved by the methylation reaction of indole.
-A common preparation method is to react indole with methanol and sulfuric acid under appropriate conditions, and then partially reduce the carboxylic acid in the produced product to alcohol under the action of alkali.
Safety Information:
-7-Methoxy-1H-indole-3-carboxylic acid is a chemical that needs to be stored properly and handled in accordance with relevant regulations.
-Appropriate personal protective measures should be taken during use, preparation or storage, such as wearing protective glasses, chemical-resistant gloves and protective clothing.
-The compound is irritating to the eyes and skin, and direct contact should be avoided.
-If the substance is inhaled or ingested, seek medical attention immediately and provide details of the compound.
-Incident handling and waste disposal should follow proper chemical handling procedures and regulations.
Last Update:2024-04-09 02:00:41